Diindolylmethane (DIM) and sulforaphane are two bioactive compounds derived from cruciferous vegetables. Initially, glucosinolates are present in broccoli and other crucifers, which are then transformed into active molecules such as sulforaphane and indole-3-carbinol (I3C). Subsequently, I3C converts into DIM. This conversion process is catalyzed by the enzyme myrosinase, which is activated during chewing or secreted by our microbiota during digestion. To form DIM, a second transformation occurs in the stomach, where indole-3-carbinol undergoes dimerization under gastric acidity, meaning two I3C molecules bond together to create a DIM molecule. As humans age, significant hormonal changes occur, affecting various biological processes, including aromatization. Aromatization is an enzymatic process in which the enzyme aromatase converts certain androgens, such as testosterone, into estrogens. While this mechanism is natural and essential for hormonal balance, it can become problematic with aging. In men, for instance, increased aromatase activity can lead to a lower testosterone-to-estrogen ratio. This hormonal imbalance is often associated with adverse effects, such as benign prostatic hyperplasia, reduced muscle mass, increased fat mass, decreased libido, and mood disturbances. In women, although aromatization becomes less central after menopause, it can negatively affect certain estrogen-sensitive tissues, such as the breasts.
This phenomenon can also be exacerbated by lifestyle factors, such as excess body weight, since adipose (fat) tissue is a significant source of aromatase production. Therefore, an increase in body fat can amplify the aromatization process, intensifying age-related hormonal imbalances.
While aromatization is a natural process, its amplification with age can contribute to hormonal imbalances that impact overall health and well-being.
Why choose PHYSIOMANCE® DIM ?
PHYSIOMANCE® DIM is designed to meet the needs of precise and personalized supplementation. This supplement is mono-ingredient, allowing it to be easily combined with other products without the risk of overdosing. With a 100% natural composition, free from excipients, and in plant-based capsules, it ensures optimal quality suitable for everyone. Our young broccoli sprout extract is a concentrate of exceptional quality, developed through a rigorous standardization process. With an extraction ratio of 30:1, each serving is equivalent to 30 grams of dried plant material, concentrated into just 2 capsules. This extract is precisely standardized to 20% diindolylmethane (DIM) and 10% sulforaphane, ensuring an optimal concentration of active ingredients.
The dosage has been carefully calibrated to provide the perfect balance: 2 capsules deliver 200 mg of diindolylmethane and 100 mg of sulforaphane, ensuring maximum efficacy. This unique formulation highlights the benefits of young broccoli sprouts while offering exceptional concentration for natural and targeted support.
What does science say ? DIM and sulforaphane are the subject of extensive scientific research, and their biological mechanisms of action are well-documented in the literature. Numerous studies highlight their potential applications in health and prevention. However, to date, European legislation has not approved any health claims for DIM and sulforaphane. Although no specific benefits are officially recognized, these molecules are generating growing interest and offer promising prospects that deserve further exploration.
Key benefits of PHYSIOMANCE® DIM
Derived from Young Broccoli Sprouts Young broccoli sprouts contain significantly higher concentrations of glucosinolates, including glucobrassicin, the precursor to DIM, compared to mature broccoli. Due to their active metabolism, these sprouts concentrate the essential elements needed for the plant's growth, explaining their unique nutritional profile and purity. When subjected to a standardized and controlled extraction process, they yield highly pure indole-3-carbinol, a bioactive compound that can subsequently be converted into diindolylmethane (DIM).
Carefully selected and processed using respectful extraction methods, young broccoli sprouts produce a pure extract, free from excipients and contaminants. This purity ensures high bioavailability, meaning optimal absorption by the body, allowing DIM to fully exert its beneficial biological effects.
The young broccoli sprout extract used in our formulations is obtained through a standardized and highly concentrated extraction process, designed to ensure the purity and richness of bioactive compounds. This rigorous process isolates and preserves the compounds of interest, particularly glucosinolates, the precursors to DIM and sulforaphane, while maintaining their integrity and bioavailability.
Clinically Studied Dosages
PHYSIOMANCE® DIM combines the natural power of young broccoli sprouts with a carefully crafted formulation based on scientifically studied doses. Thanks to advanced extraction techniques and rigorous standardization, this product ensures superior quality and perfectly addresses individual needs.
This concentrate highlights two active ingredients with scientifically recognized benefits: diindolylmethane (DIM) and sulforaphane. Sourced from young broccoli sprouts, these bioactive compounds are obtained through an exceptional extraction process with a 30:1 ratio. This means that two capsules contain the equivalent of the richness found in 30 grams of dried plant material, ensuring an optimal concentration of active compounds.
Our extracts are standardized to deliver precise levels of these valuable compounds: 20% DIM, a molecule naturally formed during the digestion of cruciferous vegetables, and 10% sulforaphane.
Formulated with optimal dosages, this supplement provides 200 mg of DIM per serving and 100 mg of sulforaphane—key bioactives that scientific research has shown to have numerous promising applications.
Rigorous Standardization Thanks to a standardized extraction process, PHYSIOMANCE® DIM ensures exceptional purity and optimal richness in bioactive compounds. Every step of the manufacturing process adheres to the strict criteria established by the European Pharmacopoeia, guaranteeing maximum safety and efficacy.
This dietary supplement reflects our commitment to providing a high-quality product that meets the most stringent standards in health and wellness.
Guaranteed Naturalness PHYSIOMANCE® DIM also stands out for its commitment to naturalness. Entirely pure and vegan, it contains no excipients or controversial additives, making it a safe and health-conscious choice.
The selected active ingredients are of impeccable quality, ensuring optimal safety for confident use.
Using advice
1 to 2 capsules per day.
Directions for use:
For people with hypothyroidism or undergoing thyroid treatment, consult your doctor.
Food supplements should be used as part of a healthy lifestyle and must not be used as a substitute for a varied and balanced diet. Do not exceed recommended daily dose. Keep this product out of the reach of young children.
If using several dietary supplements, ask your healthcare professional for guidance.
Quality commitment guaranteeing natural formulas, from active ingredients to excipients, without artificial colouring or flavouring, without aspartame, without titanium dioxide, without GMOs, without nanoparticles, without irradiation, without colloidal silica, without preservatives, not tested on animals and made in Europe.
Quality label registered by the THERASCIENCE Laboratory, guaranteeing the origin, selection, bacteriological quality and effectiveness of all the plant extracts.
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