According to the WHO, one in six people is affected by infertility, which is approximately 17.5% of the global adult population. Infertility, beyond its medical dimension, has significant repercussions on the lives of those who suffer from it.
Fertility and ovarian function are fundamental aspects of the female reproductive system. The ovaries play a crucial role in regulating the menstrual cycle and producing eggs, the reproductive cells necessary for conception. Each month, during ovulation, one of the ovaries releases a mature egg: it is precisely at this moment that the egg is ready to be fertilized. At the same time, the ovaries produce hormones such as estrogen and progesterone, which influence the ovulation cycle and prepare the uterus for pregnancy. A woman's fertility depends on the regularity of her menstrual cycles, the quality of her eggs, and the overall hormonal functioning of the body.
The link between fertility, hormone levels, and insulin levels is an important aspect of female reproductive health. Insulin is a hormone produced by the pancreas that regulates blood sugar levels. However, high insulin levels, often associated with insulin resistance and abnormally high blood glucose levels, can disrupt hormonal balance, leading to irregular menstrual cycles, ovulation disorders, and symptoms such as acne, excessive hair growth, and weight gain. For women, insulin resistance is particularly concerning, as it is linked to conditions such as gestational diabetes and polycystic ovary syndrome (PCOS). Gestational diabetes affects about 10% of pregnancies, while PCOS affects 5% to 10% of women of reproductive age, and both are exacerbated by insulin resistance. PHYSIOMANCE® SOPK is a solution specifically developed with chromium, which helps maintain normal blood sugar levels, and vitamins B9 and B12, which contribute to the normal growth of maternal tissues during pregnancy and the normal metabolism of homocysteine.
Why choose PHYSIOMANCE® SOPK ?
PHYSIOMANCE® SOPK offers an innovative and effective solution. Its formula is based on a synergistic combination of rigorously selected active ingredients.
This formulation combines 3 g of natural Myo-Inositol with 330 mg of D-Chiro-Inositol and also includes 75 mg of aronia extract, equivalent to 300 mg of dry plant, as well as optimized levels of vitamins B9 and B12 and chromium, dosed at 150% of the reference intake.
The choice of bioavailable ingredients ensures optimal absorption and enhanced effectiveness. Thus, chromium is used in the form of picolinate, while vitamins B9 and B12 are included in their coenzyme forms, directly usable by the body.
As part of a quality approach and commitment to naturalness, PHYSIOMANCE® SOPK has been formulated without excipients and is packaged in 100% plant-based capsules, making it suitable for a vegetarian or vegan diet.
What does science say?
The bioactive ingredients present in PHYSIOMANCE® SOPK have undergone thorough scientific evaluation by the European Food Safety Authority (EFSA).
- - Vitamins B9 and B12 contribute to the growth of maternal tissues during pregnancy, the normal metabolism of homocysteine, the process of cell division, and the reduction of fatigue.
- - Chromium helps maintain normal blood sugar levels.
Myo-inositol, D-chiro-inositol, and aronia have been the subject of extensive scientific research, and their biological mechanisms of action are well documented in the literature. However, to date, European legislation has not validated any health claims. Although no specific benefits are officially recognized, these active ingredients are attracting growing interest and open promising perspectives that deserve further exploration.
Key benefits of PHYSIOMANCE® SOPK
Synergistic association
- Myo-inositol and D-chiro-inositol, endogenous isomers of inositol naturally present in the ovaries
Inositols are sugars that exist in nine possible structures (isomers), naturally found in various foods such as citrus fruits, cabbage, nuts, and melon, and are also present in breast milk. These inositols are also endogenous, meaning they are naturally produced by our body. Among the 9 isomers of inositols, two are of particular interest: Myo-inositol (MI) and D-Chiro-inositol (DCI).
The myo-inositol, which is part of phospholipids, is present in cell membranes. It is the main form of inositol in the body. Its multiple health benefits make it a valuable component. Myo-inositol can then be transformed into D-chiro-inositol in the body.
The interest in these inositols mainly lies in their ability to act synergistically to maximize their health benefits, particularly in ovarian function, where they are naturally present.
PHYSIOMANCE® SOPK provides 3g of myo-inositol and 330mg of D-Chiro-Inositol for 6 capsules.
Aronia (Aronia melanocarpa) is a shrub native to North America, known for its dark purple-black berries that are particularly rich in bioactive compounds. These fruits concentrate a high level of polyphenols, particularly anthocyanins and flavonoids, with antioxidant properties. Thanks to its richness in polyphenols, aronia is a valuable source of bioactive compounds. Its properties make it a preferred ingredient in various formulations.
PHYSIOMANCE® SOPK provides 75 mg of aronia extract, equivalent to 300 mg of dry plant, for 6 capsules.
Micronutrient complex: Chromium, vitamins B9 and B12
Vitamin B12 and vitamin B9, or folic acid, are part of the B vitamin complex, classified as "water-soluble" (soluble in water). They are not stored by the body, making it crucially important to ensure regular intake through diet or supplementation.
- Vitamin B9, or folic acid, is mainly found in green leafy vegetables, which is why it is called "folic," derived from the Latin "folium" meaning "leaf." Lettuce and spinach are exceptional sources of this vitamin. It is also found in significant amounts in cereals, certain cheeses, and the livers of animals such as lamb, veal, and poultry. Vitamin B9 plays a key role in the folate cycle, which is a crucial biological process for many bodily functions. The folate cycle is a process in which vitamin B9 is converted into different active forms usable by the body. The most active and functional form of vitamin B9 in the human body is called 5-methyltetrahydrofolate, abbreviated as MTHF.
- Vitamin B12, also known as cobalamin, is found almost exclusively in animal-derived products, so it is necessary for individuals with a strict vegan diet to supplement with vitamin B12. Organ meats, such as beef and poultry liver, are among the richest sources of vitamin B12. It is also found in significant quantities in fatty fish such as salmon and mackerel, red meats, eggs, and dairy products, especially aged cheeses and yogurts. Vitamin B12 plays a fundamental role in numerous biological processes, including the methylation cycle, an essential metabolic pathway involved in gene expression regulation, the production of neurotransmitters, and the synthesis of red blood cells. In its biologically active form, methylcobalamin, it is involved in amino acid metabolism and contributes to the optimal functioning of the nervous system.
The vitamins B9 and B12 play an essential role in the body by contributing to the growth of maternal tissues during pregnancy, the normal metabolism of homocysteine, and the normal functioning of the immune system. They also participate in maintaining normal psychological functions, the normal formation of blood, the cell division process, and the reduction of fatigue, thus supporting numerous biological mechanisms necessary for the proper balance of the body.
PHYSIOMANCE® SOPK provides, for 6 capsules, 150% of the reference intake of vitamin B9 in the form of calcium L-methylfolate, i.e., 300 µg, and 150% of the reference intake of vitamin B12 in the form of methylcobalamin, i.e., 3.8 µg.
Chromium is a trace element naturally present in the environment, found in various foods such as whole grains, legumes, and meats. Although present in very small amounts in the body, it plays an essential role in regulating blood sugar levels and macronutrient metabolism. In its picolinate form, its bioavailability is optimized, allowing for effective absorption by the body. It thus contributes to the maintenance of normal blood sugar levels by enhancing the action of insulin, a key hormone in managing sugars and blood glucose. Indeed, chromium contributes to the maintenance of normal blood sugar levels.
PHYSIOMANCE® SOPK provides, for 6 capsules, 150% of the reference intake of chromium in the form of picolinate, i.e., 60 µg.
Optimal Bioavailability
THERASCIENCE Laboratory prioritizes active ingredients in their most bioavailable forms for better absorption and assimilation in the body. Bioavailability is the amount of a substance that reaches the bloodstream or the site of action in the body after being administered or consumed. This is why we systematically choose coenzymated vitamins, minerals in the form of organic salts, and bioactive compounds that are directly assimilable by the cells.
The chromium used in PHYSIOMANCE® SOPK is in the form of picolinate. In the picolinate form, the bioavailability of chromium is optimized, making its absorption by the body efficient.
The vitamins B9 and B12 used in PHYSIOMANCE® SOPK are in their coenzymated forms. Coenzymated vitamins offer numerous advantages over non-coenzymated forms. They have optimal and superior absorption by the body, thus ensuring better bioavailability, which guarantees their immediate activation and eliminates the need for further transformation once in the body. Therefore, they can be immediately used in metabolic reactions, resulting in enhanced effectiveness. Furthermore, coenzymated vitamin forms are more stable than non-coenzymated forms, ensuring the preservation of their biological activity over time.
Providing vitamins directly in their coenzymated form also allows for rapid correction of their deficiencies, offering a more effective approach to supply the body with essential elements for many metabolic reactions, while ensuring significant advantages in terms of absorption, efficiency, and stability.
In PHYSIOMANCE® SOPK, vitamin B9 is in the form of calcium L-methylfolate, vitamin B12 is in the form of methylcobalamin, and chromium is in the form of picolinate.
A Formula with Enhanced Naturalness
Give yourself the best with PHYSIOMANCE® SOPK, a natural formula that respects the THERASCIENCE® Clean label! With this label, we commit to providing natural formulas, from the choice of active ingredients to the excipients, without artificial coloring or flavoring, without aspartame, without titanium dioxide, without GMOs, without nanoparticles, non-irradiated, without colloidal silica, without preservatives, cruelty-free, and manufactured in Europe.
Furthermore, we pay particular attention to the origin of our plant, mushroom, and algae extracts, their bacteriological quality, and the effectiveness of these extracts. This is why we have developed the High Quality Process®, a method patented by our Laboratory that guarantees the origin, quality, and effectiveness of all selected plant, mushroom, and algae extracts.
In PHYSIOMANCE® SOPK we have selected a natural Myo-inositol derived from the hydrolysis of phytic acid from corn.
Additionally, THERASCIENCE Laboratory adapts to all dietary habits: PHYSIOMANCE® SOPK is guaranteed gluten-free and lactose-free.
PHYSIOMANCE® SOPK a has been designed with a 100% plant-based capsule shell.
HPMC (hydroxypropyl methylcellulose or hypromellose) is the main material used to form the shell of the vegetarian capsules. HPMC is a derivative of cellulose, a natural substance found in the cell walls of plants. It is widely used in the formulation of dietary supplements due to its remarkable properties and safety for health, offering an effective alternative to traditional gelling agents of animal or chemical origin. One of the main attractions of HPMC is its biodegradability, making it an environmentally friendly choice compared to other coating materials. By using HPMC as an excipient, THERASCIENCE Laboratory guarantees not only the safe and effective administration of the product but also addresses growing consumer concerns about quality, safety, and sustainability.
Recommandé par mon médecin, je l'utilise régulièrement, avec de tvoir plus
Avis du 28/09/2024, suite à une expérience du 11/09/2024 par Silvia S