Resolvins
Description
Resolvins are pro-resolving mediators, also known as SPMs (Specialized Pro-Resolving Mediators), which belong to the omega-3 family and have an anti-inflammatory role.
Resolvins are synthesised from EPA and DHA through various enzymatic reactions during which intermediate precursors, the pre-resolvins, are formed.
Several pre-resolvins exist, including 18-HEPE (18-hydroxy-eicosapentaenoic acid), 17-HDHA (17-hydroxy-docosahexaenoic acid) and 14-HDHA (14-hydroxy-docosahexaenoic acid).
Inflammation is a normal biological process. It consists of an initial phase in which pro-inflammatory mediators are released and inflammation increases, and a resolution phase in which inflammation is reduced and then ended by the presence of pro-resolving mediators.
While acute inflammation is essential and constitutes the body's first line of defence in the event of a tissue attack, the induction of the resolution stage by resolvins ensures a return to a pre-inflammatory physiological state, limits inflammation over time and thus prevents the transition to a chronic inflammatory state.
Benefits
Resolvins are lipid molecules involved in the process of resolving inflammation and are derived from the natural enzymatic biotransformation of precursors (18-HEPE, 17-HDHA and 14-HDHA) belonging to the omega-3 family.
THERASCIENCE Specific features
THERASCIENCE Laboratory has selected a fish oil with a high content of pre-resolvins and dosed with 18-HEPE, 17-HDHA and 14-HDHA. With the objective to preserve the world's fish stocks, Laboratoire THERASCIENCE's fish oils have been awarded the Friend of the sea©, label, a guarantee of eco-responsible fishing that cares for the environment.
Publications scientifiques
Resolvines are the subject of over 919 scientific publications.
The selection of our active ingredients is constantly guided by numerous scientific publications, based on randomised double-blind placebo-controlled clinical studies in humans, guaranteeing a real scientific value. The doctors, pharmacists and engineers of the THERASCIENCE Laboratory have selected some of these publications for you:
- So, Jisun et al. EPA and DHA differentially modulate monocyte inflammatory response in subjects with chronic inflammation in part via plasma specialized pro-resolving lipid mediators: A randomized, double-blind, crossover study. . Atherosclerosis vol. 316 (2021): 90-98 ;
- Ramirez, Joel L et al. Fish Oil Increases Specialized Pro-resolving Lipid Mediators in PAD (The OMEGA-PAD II Trial)..” The Journal of surgical research vol. 238 (2019): 164-174.
Our products based on Resolvins
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£42.44
